In institutional retrospective DUR, which two situations trigger its use?

• A. Drug Removed from Pharmacy/Contingency Stock; Override Medications
• B. Prescriber Orders; Patient Allergies
• C. New Drug Approvals; Labeling Changes
• D. Routine Refills; High-Risk Medications

Answer: (A)

Retrospective Drug Utilization Review analyzes how medications were actually used after they’ve been dispensed, looking for safety issues, inappropriate use, or deviations from guidelines based on post-dispensing data. The two triggers described are: first, when a drug is removed from the pharmacy or contingency stock, indicating it has left inventory and will be used for a patient; and second, when medications are overridden, meaning a safety alert or check was bypassed and dispensing proceeded despite potential risk. These events generate data for later review to confirm proper use, documentation, and safety, and to identify where policies or education may need to be improved. Other options involve pre-dispensing checks or unrelated regulatory updates, which are not the typical retrospective triggers.