Does the 14-day fill limit apply to refills of Schedule III–V opioids?

• A. Yes, for all refills
• B. No, only on the first fill
• C. Yes, but only for the first refill
• D. Only with physician approval

Answer: (B)

The key idea here is that the 14-day limit is about the first dispensing, not every time a prescription is refilled. For Schedule III–V opioids, the rule constrains how long the initial supply can be dispensed in a single fill. Once that first fill has occurred, refills follow the standard policies for these substances and aren’t automatically restricted by the 14-day limit. In other words, the 14-day cap applies only to the initial fill, not to all subsequent refills.